Publications
- Kriger, S. M., Spiconardi, J., Ennist, N., and Glazer, E. C. (2026). “Probing the molecular determinants of emission enhancement in RNA aptamer–metal complex systems.” Photochemistry and Photobiology. 00:1-14. doi:10.1111/php.70130
- Yang, W., Wang, S., Lee, G. R., Zhang, J. Z., Courbet, A., Juergens, D., Wang, X., Schlichthaerle, T.,Abedi, M., Ragotte, R., An, L., Kalvet, I.’ Pellock, S., Mihaljevic, L., Glasscock, C., Pillai, A., Broerman, A., Ennist, N., Haefner, E., McNamara-Bordewick, N., Haydon, I., Stewart, L., Bhardwaj, G., and Baker, D. (2026). “The past, present and future of de novo protein design.” Nature. 652;1139-1152. doi:10.1038/s41586-026-10328-7
- Ennist, N. M., Wang, S., Kennedy, M. A., Curti, M., Sutherland, G. A., Vasilev, C., Redler, R. L., Maffeis, V., Shareef, S., Sica, A. V., Hua, A. S., Deshmukh, Moyer, A. P., Hicks, D. R., Swartz, A., Cacho, R. A., Novy, N., Bera, A. K., Kang, A., Sankaran, B., Johnson, M. P., Phadkule, A. A., Reppert, M., Ekiert, D., Bhabha, G., Stewart, L., Caram, J. R., Stoddard, B. L., Romero, E., Hunter, C. N., and Baker, D. (2024). “De novo design of proteins housing excitonically coupled chlorophyll special pairs.” Nature Chemical Biology. doi:10.1038/s41589-024-01626-0
- Kalvet, I., Ortmayer, M., Zhao, J., Crawshaw, R., Ennist, N. M., Levy, C., Roy, A., Green, A. P., and Baker, D. (2023). “Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site.” Journal of the American Chemical Society 145(26), 14307-14315. doi:10.1021/jacs.3c02742
- Ennist, N. M., Zhao, Z., Stayrook, S. E., Discher, B. M., Dutton, P. L., and Moser, C. C. (2022). “De novo protein design of photochemical reaction centers.” Nature Communications 13(1), 4937. doi:10.1038/s41467-022-32710-5
- Ennist, N. M., Stayrook, S. E., Dutton, P. L., and Moser, C. C. (2022). “Rational design of photosynthetic reaction center protein maquettes.” Frontiers in Molecular Biosciences, 9. doi:10.3389/fmolb.2022.997295
- Ennist, N. M., Mancini, J. A., Auman, D. B., Bialas, C. P., Iwanicki, M. J., Esipova, T. V., Discher, B. M., Moser, C. C., and Dutton, P. L. (2017). “Maquette Strategy for Creation of Lightand Redox-Active Proteins.” Photosynthesis and Bioenergetics. Ed. Barber, J. and Ruban, A.V. World Scientific Publishers. doi:10.1142/9789813230309_0001
- Moser, C. C., Ennist N. M., Mancini, J. M., and Dutton, P. L. (2017). “Making Maquette Models of Bioenergetic Structures.” Mechanisms of Primary Energy Transduction in Biology. Ed. Wikström, Marten: Royal Society of Chemistry. doi:10.1039/9781788010405-00001
- Moser C. C., Sheehan M. M., Ennist N. M., Kodali G., Bialas C. P., Englander M. T., Discher, B.M., and Dutton, P. L. (2016). “De Novo Construction of Redox Active Proteins.” Methods in Enzymology 580, 365-88. doi:10.1016/bs.mie.2016.05.048
- Farid, T. A., Kodali, G., Solomon, L. A., Lichtenstein, B. R., Sheehan, M. M., Fry, B. A., Bialas, C., Ennist, N. M., Siedlecki, J. A., Zhao, Z. Y., Stetz, M. A., Valentine, K. G., Anderson, J. L. R., Wand, A. J., Discher, B. M., Moser, C. C., and Dutton, P. L. (2013). “Elementary Tetrahelical Protein Design for Diverse Oxidoreductase Functions.” Nature Chemical Biology 9(12), 826-833. doi:10.1038/nchembio.1362
- Lichtenstein, B. R., Farid, T. A., Kodali, G., Solomon, L. A., Anderson, J. L. R., Sheehan, M. M., Ennist, N. M., Fry, B. A., Chobot, S. E., Bialas, C. P., Mancini, J. A., Armstrong, C. T., Zhao, Z. Y., Esipova, T. V., Snell, D., Vinogradov, S. A., Discher, B. M., Moser, C. C., and Dutton, P. L. (2012). “Engineering Oxidoreductases: Maquette Proteins Designed from Scratch.” Biochemical Society Transactions 40(3), 561-566. doi:10.1042/BST20120067
Last Reviewed On: 7/31/2026